EXPERT WORKSHOP PSLT2019-01-26T13:44:02+00:00


APRIL 1st & 2nd 2019-EDINBURGH (UK)

The recent classifications of titanium dioxide and carbon black (intended in 2021) and the suggestion that PSLTs (Poorly Soluble Low Toxicity Particles) can be considered as a group for safety classification, raises important questions how best to apply the wealth of inhalation toxicology and epidemiology information developed over the past 30 years.  In 2018, we conducted a series of 1:1 interviews with experts from the toxicology, epidemiology and regulatory fields to understand their views on topics of PSLT safety including: the definition of PSLTs; lung clearance overload; and, the implications of animal and epidemiological studies.  It was clear from our work that experts share many science-based opinions on these topics and, that also important differences exist.  Given our observations and the wide-spread use of PSLTs, it is important to have a open forum where experts can discuss the state-of-the-art science on PSLT safety and document where agreement and where differences exist.  The PSLT workshop will seek consensus on these important topics, thereby ensuring that the best science is used to evaluate the safety of inhaled particulate materials.



  • Panel of 15-20 of the top experts from across academia, regulatory, and industry
  • Invited participants only
  • Open issues discussed and debated by the experts documenting for which topics there is consensus and where disagreement exists
  • Q & A sessions will be recorded and shared

  • Publish the outcome as a state-of-the-art expert opinion paper
  • Moderation and coordination by Driscoll & Borm
  • Observers from all stakeholders including industry and regulatory field



Selecting Edinburgh as location of the workshop pays tribute to the great contribution of the Institute of Occupational Medicine (IOM), which celebrates its 50th anniversary, and distinguished academic institutes in Edinburgh in the field of occupational medicine and particle-induced lung diseases. The IOM, Edinburgh Lung and the Environment Group Initiative (ELEGI) and Heriot-Watt University are prestigious members of the inhaled particle community and have hosted many EU meetings, inhaled particle meetings and many other (public) events to raise awareness and foster the exchange of scientific information in the field of inhalation toxicology.

Academic and industrial sponsors

Local conference secretariat:

Mrs Sonia J Rafferty assistant to Rodger Duffin.
Tel: +44 (0)131 242 6582

Contact Press and Media:

Paul J.A. Borm   +31 – 6 41 72 5  51
Kevin E. Driscoll

Local organizing committee:

Dr Rodger Duffin
Centre of Inflammation research, QMRC-UoE
Dr Craig Poland

Centre of Inflammation research, QMRC-UoE
Dr Lang Tran

IOM, Edinburgh

Organizing and Planning Committee:

Dr Rodger Duffin, dr Lang Tran
Dr Len Levy (Cranfield University)
Dr Thomas Gebel (BaUA)
Dr Kevin E. Driscoll (Rutgers University, NY)
Prof. dr. Paul J.A. Borm ( Nanoconsult)