It does not come as a surprise that the COVID-19 virus behaves as a nanoparticle that upon inhalation can deposit in the nasal cavity and cross the one cell-layer olfactory epithelium to reach the brain and cause damage. A recent case in a radiology technician shows how MRI is able to detect brain changes upon infection with the virus. Follow-up studies are being performed on the long-term effect of the CSARS-CoV-2 in the brain. and preliminary evidence is present hat thromboembolisms and vasculitis/endothelin alterations are present in the brain.